Antimicrobial effect of some herbal medicine against infectious bacteria isolated from burn wound

Document Type: Research(Original) Article


1 Plastic Surgery Ward, School of Medicine, Shahid Beheshti University of Medical Sciences

2 Agricultural and Natural Resources College, Persian Gulf University, Bushehr, Iran

3 Burn and Wound Healing Research Center, Shiraz University of Medical Science, Shiraz, Iran

4 Legal Medicine Research Center, Legal Medicine Organization of Iran, Tehran, Iran


Herbal compounds with antimicrobial effects are of major considerations because of increasing antimicrobial resistance of pathogenic bacteria. In this study, we investigated the antimicrobial effects of Melissa officinalis L, Plantago major L, Orobancha crenata Forsk, Phoenix dactylifera, Ziziphus mauritiana and Teucrium Polium seed extracts on some human pathogenic bacteria isolated from burn wounds. Disk-diffusion antibiotic sensitivity testing, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were applied to assess the antibacterial activity of the extracts in comparison to the tetracycline, as a control antibiotic. The extract of the Orobancha crenata showed stonger antibacterial effects than the other herbal extracts on Pseudomonas aeroginosa and Kelebsiela ponomoni. Staphylococcus aureus was the most sensitive one to the Ziziphus mauritiana nucleus extract compared to other herbs. According to the results of this study, it can be concluded that extracts of some native plants of Iran can be appropriate alternative to the existing antibiotics, applicable for prevention of burn infections.


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