Antimicrobial effect of some herbal medicine against infectious bacteria isolated from burn wound

Shahin Mohammadsadeghi, Hasan Habibi, Abdorrasoul Malekpour


Because of increasing of antimicrobial resistance of pathogenic bacteria, researchers are seeking on new herbal compounds as an alternative to chemical drugs and antibiotics. This study investigated the antibacterial effect of Melissa officinalis L, Plantago major L, Orobancha crenata Forsk, Phoenix dactylifera, Ziziphus mauritiana and Teucrium Polium seed extracts on some human pathogenic bacteria isolated from burn wound. Disk-diffusion antibiotic sensitivity testing, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were used to evaluate the antibacterial activity of plant extracts in comparison to the tetracycline, as a control antibiotic. The underlying results indicated strong antimicrobial effects of the extracts against tested bacteria. Extract of the Orobancha crenata showed stonger antibacterial effects than the other herbs on Pseudomonas aeroginosa and Kelebsiela ponomoni. Staphylococcus aureus was the most sensitive to the Ziziphus mauritiana nucleus extract compared to other herbs. According to the results of this study, it can be concluded that extracts of some Iranian native plants can be appropriate alternative to the existing antibiotics.


Melissa officinalis, Teucrium Polium, Burn infections, pathogenic bacteria



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