Recent creative innovations for modernizing traditional medicine

Document Type : Opinion

Authors

1 Phytopharmaceutical Technology and Traditional Medicine Incubator, Shiraz University of Medical Sciences, Shiraz, Iran

2 Department of Traditional Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.

Abstract

< p>Traditional medicine with a profound historical background is a rich source of clinical experiences for thousands of years. It has shown promising therapeutic effects on complex disorders with a holistic approach. However, the multi-component and multi-target pharmacology of traditional drugs are not clearly understood with the current reductionist approach. Modernization of traditional medicine (TM) by means of modern technology and academic thoughts as well as innovative methods and scientific experiments helps better perception of the ancient wisdom behind traditional mechanisms. Besides, modernization of TM via new ideas from the globally accepted scientific standards can result in a series of highly active, safe, and controllable modern TM products. In this approach, advanced technology and innovative methodology play a key role in TM development. On the other hand, personalized medicine paradigm which is recommended in TM theories aims to achieve the proper diagnosis and treatment for each patient. It particularly focuses on the maintenance of health and enhancing the resistance of body to diseases. The present work was conducted to emphasis the pivotal role of utilizing modern innovations in TM systems

Keywords


1. Li WF, Jiang JG, Chen J. Chinese medicine and its modernization demands. Arch Med Res. 2008 Feb;39(2):246-51. doi: 10.1016/j.arcmed.2007.09.011. Epub 2007 Nov 26. PMID: 18164973.
2. Zhang A, Sun H, Wang P, Han Y, Wang X. Future perspectives of personalized medicine in traditional Chinese medicine: a systems biology approach. Complement Ther Med. 2012 Feb-Apr;20(1-2):93-9. doi: 10.1016/j.ctim.2011.10.007. Epub 2011 Nov 30. PMID: 22305254.
3. Beauregard M, Dyer N, Schwartz G. Toward a postmaterialist psychology: Theory, research, and applications. New Ideas Psychol. 2018; 50:21-33. doi: 10.1016/j.newideapsych.2018.02.004.
4. Tu Y. The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine. Nat Med. 2011 Oct 11;17(10):1217-20. doi: 10.1038/nm.2471. PMID: 21989013.
5. Liu X, Wu WY, Jiang BH, Yang M, Guo DA. Pharmacological tools for the development of traditional Chinese medicine. Trends Pharmacol Sci. 2013 Nov;34(11):620-8. doi: 10.1016/j.tips.2013.09.004. Epub 2013 Oct 16. PMID: 24139610.
6. Kim HU, Ryu JY, Lee JO, Lee SY. A systems approach to traditional oriental medicine. Nat Biotechnol. 2015 Mar;33(3):264-8. doi: 10.1038/nbt.3167. PMID: 25748918.
7. Lao YM, Jiang JG, Yan L. Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine. Br J Pharmacol. 2009 Aug;157(7):1128-41. doi: 10.1111/j.1476-5381.2009.00257.x. Epub 2009 Jun 5. PMID: 19508399; PMCID: PMC2743831.
8. Fung H-N, Wong C-Y. Exploring the modernization process of traditional medicine: a Triple Helix perspective with insights from publication and trademark statistics. Soc Sci Inf. 2015;54(3):327-353. doi:10.1177/0539018415577504
9. Jiang M, Yang J, Zhang C, Liu B, Chan K, Cao H, Lu A. Clinical studies with traditional Chinese medicine in the past decade and future research and development. Planta Med. 2010 Dec;76(17):2048-64. doi: 10.1055/s-0030-1250456. Epub 2010 Oct 26. PMID: 20979016.